Dr. Alexander Lippert
The following report presents the work done by Kevin Bruemmer for his Engaged Learning project. The 19F magnetic resonance probes 5-uoroisatin and 6-uoroisatin were reacted with ONOO- to yield anthranilic acid derivatives through a novel oxidative decarbonyaltion reaction. Utilizing 19F NMR spectroscopy techniques, the presence of ONOO- can be determined through a chemical shift switching signal. 5-uoroisatin was subsequently used to detect ONOO- in living lung epithelial cells.
Engaged Learning 2014, x-ray detector, silicon PIN diode, circuit
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Bruemmer, Kevin, "The Detection of Peroxynitrite Using 19F Magnetic Resonance Probes" (2014). Collection of Engaged Learning. 63.