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Theses/Dissertations from 2024

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A Genetic Screen to Identify Cell-Specific Inhibitors of Microexon Splicing in the unc-13 Transcript in C. elegans, Saad Ali

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SCREEN FOR BENEFICIAL GENETIC AND CHEMICAL MODIFIERS IN DROSOPHILA MODELS OF ALS AND TRAUMATIC BRAIN INJURY, Will Bonderer

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Dissecting The Tissue-Specific Contributions To Seizures, Cardiorespiratory Dysfunction, And Sudden Death In The Kv1.1 Mouse Model Of Epilepsy Using Conditional Knockout Approaches, Kelsey Paulhus

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The Tissue-Specific Role of smn-1 in C. elegans, Lindsey Philips

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Unveiling the Nexus of Cellular Quality Control: Exploring the Interplay Between Ribosome-Associated Protein Quality Control and Mitochondrial Quality Control Pathways, Foozhan Tahmasebinia

Theses/Dissertations from 2023

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Regulation of mRNA and circRNA as a Cause and Consequence of Aging in Caenorhabditis elegans, Rebekah Napier-Jameson

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Dynamics and Inhibition of ABC and RND Transporters Associated with Multidrug Resistances in Cancer and Pathogenic Bacteria, Hang Zhao

Theses/Dissertations from 2022

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Assembly of the Peripheral Arm Subunits of Escherichia coli Complex I and Analysis of Clinical Mutations, Hind Alkhaldi

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The Roles of Individual Proteins in De Novo Recruitment of PcG Repressive Complexes to Giant, Anni Kum

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Modulation of p53-Dependent Differentiation Signaling Through Molecular Interactions Between the HPV E6 Oncoprotein and the Actin-Binding Transcriptional Cofactor, MKL1, Nicholas Kurtaneck

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Regulation and Function of the MEC-8/RBPMS RNA Binding Protein in vivo, Xiaoyu Liang

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Dissecting Interactions Across Gene Regulatory Layers in C. elegans, Morgan Taylor

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Activation of p53-Regulated Pro-survival Signals and Hypoxia-Independent Mitochondrial Targeting of TIGAR by E6 Oncoproteins of High-Risk HPVs, Lacin Yapindi

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Roles of Individual Protein in de novo Polycomb Protein Recruitment, Piao Ye

Theses/Dissertations from 2021

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Dynamic Mechanisms Of Multidrug Resistance In Human Cancers And Gram Negative Pathogens, Lauren Ammerman

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Mechanistic Studies of Drug-Like Inhibitors of P-glycoprotein Using ATPase Assays, Electron Spin Resonance Spectroscopy and Cancer Cell Models, Gang Chen

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Biochemical Evaluation of Drug Inhibition of ABC Transporters, Maisa Correa de Oliveira

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The Analysis of Assembly Pathway and Clinical Mutations of the Membrane Arm Subunits of Escherichia Coli Complex I, Fang Zhang

Theses/Dissertations from 2020

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Determining how the Human T-cell Leukemia Virus Type-1 (HTLV-1) Latency-Maintenance Factor p30ll Modulates Antioxidant- Signaling to Promote Oncogene Activation during Retroviral Carcinogenesis, Tetiana Bowley

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In Vitro Reversal and Characterization of Multidrug Resistance in Human Cancer Cells, Kasi Holcomb-Webb

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RelA/p65 Blocks Histone Deacetylase-3 Neurotoxicity and Protects Neurons Against Neuronal Death Induced by PolyQ-Expanded Huntingtin and Ataxin-1 in a p65 Phospho S276 Dependent Manner, Yiyu Zhang

Theses/Dissertations from 2019

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Peroxiredoxin 6 and Phospholipids in Alzheimer's Disease, Nathan A. Drolet

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Peroxiredoxin 6 and Inflammation in Alzheimer's Disease, Jared Ferrell-Penniman

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Recruitment of Polycomb-Group Proteins at giant in Drosophila Embryos, Elnaz Ghotbi Ravandi

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HTLV-1 Latency-Maintenance Factor p30II Modulates Tax-Induced NF-kappa B Signaling Through a p53-Regulated Mechanism, Aditi Malu

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Reversal of P-Glycoprotein and Breast Cancer Resistance Protein Mediated Multidrug Resistance In Vitro Using In Silico Identified Novel Compounds, Amila Nanayakkara

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Reversal of P-Glycoprotein and Breast Cancer Resistance Protein Mediated Multidrug Resistance In Vitro Using In Silico Identified Novel Compounds, Amila Nanayakkara