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Biological Sciences Theses and Dissertations

Theses/Dissertations from 2024 2024

A Genetic Screen to Identify Cell-Specific Inhibitors of Microexon Splicing in the unc-13 Transcript in C. elegans, Saad Ali

SCREEN FOR BENEFICIAL GENETIC AND CHEMICAL MODIFIERS IN DROSOPHILA MODELS OF ALS AND TRAUMATIC BRAIN INJURY, Will Bonderer

Regulation and Function of mec-2 Alternative Splicing in Single Cells, Canyon Calovich-Benne

Reversing Cancer Multidrug Resistance in vitro, Jesiska Lowe

Dissecting The Tissue-Specific Contributions To Seizures, Cardiorespiratory Dysfunction, And Sudden Death In The Kv1.1 Mouse Model Of Epilepsy Using Conditional Knockout Approaches, Kelsey Paulhus

The Tissue-Specific Role of smn-1 in C. elegans, Lindsey Philips

Unveiling the Nexus of Cellular Quality Control: Exploring the Interplay Between Ribosome-Associated Protein Quality Control and Mitochondrial Quality Control Pathways, Foozhan Tahmasebinia

Theses/Dissertations from 2023 2023

Regulation of mRNA and circRNA as a Cause and Consequence of Aging in Caenorhabditis elegans, Rebekah Napier-Jameson

Dynamics and Inhibition of ABC and RND Transporters Associated with Multidrug Resistances in Cancer and Pathogenic Bacteria, Hang Zhao

Theses/Dissertations from 2022 2022

Assembly of the Peripheral Arm Subunits of Escherichia coli Complex I and Analysis of Clinical Mutations, Hind Alkhaldi

The Roles of Individual Proteins in De Novo Recruitment of PcG Repressive Complexes to Giant, Anni Kum

Modulation of p53-Dependent Differentiation Signaling Through Molecular Interactions Between the HPV E6 Oncoprotein and the Actin-Binding Transcriptional Cofactor, MKL1, Nicholas Kurtaneck

Regulation and Function of the MEC-8/RBPMS RNA Binding Protein in vivo, Xiaoyu Liang

Dissecting Interactions Across Gene Regulatory Layers in C. elegans, Morgan Taylor

Activation of p53-Regulated Pro-survival Signals and Hypoxia-Independent Mitochondrial Targeting of TIGAR by E6 Oncoproteins of High-Risk HPVs, Lacin Yapindi

Roles of Individual Protein in de novo Polycomb Protein Recruitment, Piao Ye

Theses/Dissertations from 2021 2021

Dynamic Mechanisms Of Multidrug Resistance In Human Cancers And Gram Negative Pathogens, Lauren Ammerman

Mechanistic Studies of Drug-Like Inhibitors of P-glycoprotein Using ATPase Assays, Electron Spin Resonance Spectroscopy and Cancer Cell Models, Gang Chen

Biochemical Evaluation of Drug Inhibition of ABC Transporters, Maisa Correa de Oliveira

The Analysis of Assembly Pathway and Clinical Mutations of the Membrane Arm Subunits of Escherichia Coli Complex I, Fang Zhang

Theses/Dissertations from 2020 2020

Determining how the Human T-cell Leukemia Virus Type-1 (HTLV-1) Latency-Maintenance Factor p30ll Modulates Antioxidant- Signaling to Promote Oncogene Activation during Retroviral Carcinogenesis, Tetiana Bowley

In Vitro Reversal and Characterization of Multidrug Resistance in Human Cancer Cells, Kasi Holcomb-Webb

RelA/p65 Blocks Histone Deacetylase-3 Neurotoxicity and Protects Neurons Against Neuronal Death Induced by PolyQ-Expanded Huntingtin and Ataxin-1 in a p65 Phospho S276 Dependent Manner, Yiyu Zhang

Theses/Dissertations from 2019 2019

Peroxiredoxin 6 and Phospholipids in Alzheimer's Disease, Nathan A. Drolet

Peroxiredoxin 6 and Inflammation in Alzheimer's Disease, Jared Ferrell-Penniman

Recruitment of Polycomb-Group Proteins at giant in Drosophila Embryos, Elnaz Ghotbi Ravandi

HTLV-1 Latency-Maintenance Factor p30II Modulates Tax-Induced NF-kappa B Signaling Through a p53-Regulated Mechanism, Aditi Malu

Reversal of P-Glycoprotein and Breast Cancer Resistance Protein Mediated Multidrug Resistance In Vitro Using In Silico Identified Novel Compounds, Amila Nanayakkara

Reversal of P-Glycoprotein and Breast Cancer Resistance Protein Mediated Multidrug Resistance In Vitro Using In Silico Identified Novel Compounds, Amila Nanayakkara